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Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
Hamermesh, Richard G.; Kucherlapati, Raju; Gordon, RachelCase HBS-810066-EEntrepreneurshipIn May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had received approval several years prior. Moreover, Vectibix had also received Food and Drug Administration approval in 2006. During additional trials, Amgen has learned that the Vectibix...Starting at €8.20
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The Indego Africa Project (Spanish Version)
McGinn, Kathleen L.; Gordon, RachelCase HBS-914S10Dos abogados jóvenes que se encuentran y comienzan a construir el Proyecto África Indego, una asociación de ONG con cooperativas de mujeres en Ruanda. Indego conecta las cooperativas en el mercado minorista internacional de productos artesanales hechos a mano, ayuda a las cooperativas construyen su capacidad de negocio, y desarrolla y ofrece formación en el aula en la vida y habilidades de negocio para los miembros de la cooperativa. En el moment...Starting at €8.20
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Storming into the U.S. Market (Spanish version)
Bartlett, Christopher A.; Gordon, Rachel; Lafkas, JohnCase HBS-918S10StrategyThe RoboTech case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative product (a specialized surgical robot) in an unfamiliar market segment (spinal surgery) and decides to enter the unfamiliar, distant U.S. healthcare market, which is characteri...Starting at €8.20
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Intrapreneurship within FLG, Inc. (Spanish version)
Garvin, David A.; Gordon, RachelCase HBS-918S11EntrepreneurshipThis case follows Jenica Fletcher as she rebuilds her company's guitar strings division from the ground up. Convinced that she could turn the division around if given complete independence from corporate headquarters, Fletcher relocated the group, rebranded it as Malenti Strings, repositioned the guitar strings as high-performance products, and transformed Malenti into a fast-growing, profitable business. The case traces Fletcher's key steps in...Starting at €8.20
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Differences at Work: Alex (A) (Spanish version)
Sucher, Sandra J.; Gordon, RachelCase HBS-408S50Leadership and People ManagementIn Differences at Work: Alex (A), HBS Case No. 9-408-011 Alex has been asked an inappropriate question by the interviewer at an interview for his dream job. How will Alex handle the situation? Should he accept the position is offered?Starting at €8.20
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Amazon Go: Venturing into Traditional Retail
Wiboon Kittilaksanawong; Aurelia KarpCase IVEY-9B17M092-EEntrepreneurship, StrategyIn December 2016, Amazon.com, Inc. (Amazon), the largest online retailer, entered the offline retailing industry by launching its first Amazon Go store in Seattle. Previously, the company had entered the food, diaper, and housekeeping product manufacturing industries with its Amazon Elements brand. The company had not been profitable until 2001 and was still facing some financial difficulties, but it was named the fourth most valuable public comp...Starting at €8.20
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Rosetree Mortgage Opportunity Fund, Teaching Note
Perold, Andre F.; Ivashina, VictoriaTeaching Note HBS-210065-EFinanceTeaching Note for [209088].Starting at €0.00
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Oaktree and the Restructuring of CIT Group (B)
Ivashina, Victoria; Scharfstein, David S.Case HBS-214036-EFinanceThis supplement presents the actual terms of the rescue financing provided by a group of private investors to CIT. It is intended to be distributed at the end of the discussion of "Oaktree and the Restructuring of CIT Group (A)" (HBS No. 214-035) and can be used as background to reflect on the students' proposal of financing terms for the $3 billion rescue financing of CIT.Starting at €5.74
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Note on LBO Capital Structure, Module Note
Gompers, Paul A.; Ivashina, Victoria; Van Gool, JorisCase HBS-214039-EFinanceThis note discusses the capital structure often found in LBO transactions. Although the specifics of each capital structure vary case by case, in any given year, there is a great deal of similarity in the capital structure of these buyouts. These similariStarting at €8.20
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Momentive Performance Materials, Inc., Teaching Note
Ivashina, Victoria; Scharfstein, David S.Teaching Note HBS-214057-EFinanceTo maximize their effectiveness, color cases should be printed in color. Teaching note for case 210081.Starting at €0.00