Open Humans - Balancing social good with data privacy

Madeleine Ball, cofounder and Executive Director of Open Humans, received a tempting offer: a partnership with a major healthcare organization. For a nonprofit built on the radical idea of empowering individuals to share their personal health data for research, the deal promised legitimacy, funding, and scale. But it also carried risks: Would accepting it compromise Open Humans’ independence, values, and trust with its community?

Launched in 2015 out of Harvard’s Personal Genome Project, Open Humans managed a platform where participants could voluntarily donate personal data—from their Fitbit logs to their own genomes—to medical research projects. Its model championed transparency, user autonomy, and grassroots collaboration, attracting thousands of contributors and numerous research projects. The goal was to make it easier for willing donors to contribute their data while protecting their ownership, control, and safety.

This case examines the landscape of digitally driven citizen science and data donation. With the first projects appearing in the 1990s, their popularity had risen with the COVID-19 pandemic, which saw a multitude of grassroots or government-backed projects come to the fore. Yet, organizations such as Open Humans now faced mounting challenges: stricter privacy regulations (GDPR and HIPAA), rising donor skepticism about data misuse, and persistent issues of data quality and governance. Scaling the platform required resources, but resources often came with strings attached.

 

 

Collection: IESE (España)
Ref: OIT-64-E
Format: PDF
Number of pages: 15
Publication Date: Oct 15, 2025
Language: English

What material is included in this case:

Teaching Note Exclusive professors
Other supplements

Description

Madeleine Ball, cofounder and Executive Director of Open Humans, received a tempting offer: a partnership with a major healthcare organization. For a nonprofit built on the radical idea of empowering individuals to share their personal health data for research, the deal promised legitimacy, funding, and scale. But it also carried risks: Would accepting it compromise Open Humans’ independence, values, and trust with its community?

Launched in 2015 out of Harvard’s Personal Genome Project, Open Humans managed a platform where participants could voluntarily donate personal data—from their Fitbit logs to their own genomes—to medical research projects. Its model championed transparency, user autonomy, and grassroots collaboration, attracting thousands of contributors and numerous research projects. The goal was to make it easier for willing donors to contribute their data while protecting their ownership, control, and safety.

This case examines the landscape of digitally driven citizen science and data donation. With the first projects appearing in the 1990s, their popularity had risen with the COVID-19 pandemic, which saw a multitude of grassroots or government-backed projects come to the fore. Yet, organizations such as Open Humans now faced mounting challenges: stricter privacy regulations (GDPR and HIPAA), rising donor skepticism about data misuse, and persistent issues of data quality and governance. Scaling the platform required resources, but resources often came with strings attached.

 

 

Read more
Geographic Setting: United States
Industry Setting: Health

Learning Objective

This case is suitable for graduate-level courses in healthcare management, digital health, data ethics, information systems, public policy, and social entrepreneurship. It is particularly well suited for programs in which students examine the intersection of technology, ethics, and policy in digital innovation.

In particular, the case of Open Humans and the broader concept of data donation examines the following topics:

  • Understanding data ethics in healthcare: Students will explore ethical issues around personal data use, particularly in health research contexts.
  • Analyzing the privacy calculus in data donation decisions: The case and this note examine the factors individuals consider when choosing to share sensitive data, discussing trade-offs between privacy, perceived benefits, and altruistic motivations.
  • Evaluating privacy management and regulatory compliance: The case looks at frameworks such as the GDPR and HIPAA and examines how organizations can navigate complex legal landscapes.
  • Decision-making in the context of social good vs. individual rights: Students will discuss the inherent tensions between promoting public interest and protecting individual privacy.
  • Leadership and strategic choices in mission-driven organizations: The partnership scenario provided in the case will enable discussion around the strategic trade-offs between scale, sustainability, and independence for a mission-driven organization.
  • Recognizing the importance of data accuracy and curation: The case highlights the technical and operational challenges when aggregating diverse user-generated data, emphasizing the importance of having good data quality in order to extract valid knowledge from it.

 

Open Humans - Balancing social good with data privacy

Options of use
Number of copies
- +
As low as €8.53

Are you interested in this product?

Add it to your favourites so that your institution can purchase it.
You'll be able to order once your profile has been validated.
Add to wishlist

Leave your rating

"Open Humans - Balancing social good with data privacy"